These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Transient PO2 and PCO2 differences between end-tidal gas and arterial blood during rebreathing in awake dogs.
    Author: Loeppky JA, Scotto P, Piiper J.
    Journal: Respir Physiol; 1985 May; 60(2):135-44. PubMed ID: 3925516.
    Abstract:
    O2 and CO2 partial pressures in end-tidal gas (PA) and carotid artery blood (Pa) were measured during non-steady-state gas exchange in unanesthetized dogs. In 5 experiments (A), low O2 breathing in open circuit preceded prolonged rebreathing during maintained normoxia. In 6 experiments (B), steady-state hypoxia and hypercapnia were followed by rebreathing CO2 in hyperoxia which caused PAO2 to rise and then fall while PACO2 increased. Negative (Pa-PA)CO2, averaging -5 torr, were observed 10 sec after starting rebreathing in B and values between -1 and -2 torr were noted later in A and B. (PA-Pa)O2 showed considerable transient increases for 2 min in A and 20 sec in B. This behavior of (PA-Pa)O2 could be explained by a lung model with unequal distribution of alveolar ventilation and perfusion to alveolar volume. The negative (Pa-PA)CO2 values observed during rebreathing with rapidly increasing PACO2 were in part attributable to such unequal distribution effects, in part to lung-to-carotid artery transit time effects.
    [Abstract] [Full Text] [Related] [New Search]