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  • Title: [Controlled trial and cost/efficacy evaluation of the prevention of infectious complications in surgery of cancers of the upper aerodigestive tract with peri-operative cefoxitin].
    Author: Renaud-Salis JL, Lacut JY, Lakdja F, Dupon M, Faucher A.
    Journal: Ann Otolaryngol Chir Cervicofac; 1985; 102(3):179-82. PubMed ID: 3925863.
    Abstract:
    Major surgery of the cancers of the upper aerodigestive tract involves a high risk of post operative infection. We report the results of a clinical controlled trial aimed to evaluate the effectiveness and the cost of the prevention of post operative infections by peri operative cefoxitin. These results show a significant difference in favor of the treated group when considering the local infection rate (15% versus 80%) the length of healing, as well as the direct costs related to the antibiotherapy. These results have been confirmed by a further study.
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