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  • Title: Double blind comparison of short and medium term sulfonamides, sulfamethizole and sulfamethoxazole, in uncomplicated acute urinary tract infections.
    Author: Bergan T, Skjerven O.
    Journal: Scand J Infect Dis; 1979; 11(3):219-23. PubMed ID: 392739.
    Abstract:
    Sulfamethizole and sulfamethoxazole were compared in a prospective, randomized, double blind study on uncomplicated, acute urinary tract infections. 59 patients were evaluable for therapeutic effect of sulfamethizole and 53 for sulfamethoxazole. The cure rates were 91.5 and 92.5% respectively for sulfamethizole and sulfamethoxazole. The rates of side effects were the same in the two groups, 5.4% and 4.2%. Also instances where the infecting bacteria were sulfonamide-resistant were cured.
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