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  • Title: [Acute myeloblastic leukemia with involvement of the basophilic cell line and anomalies of the short arm of chromosome 12 (12p)].
    Author: Daniel MT, Bernheim A, Flandrin G, Berger R.
    Journal: C R Acad Sci III; 1985; 301(6):299-301. PubMed ID: 3928106.
    Abstract:
    Among 16 leukemia patients with abnormalities of the short arm of chromosome 12 (12p) were found 5 patients with an increased number of marrow basophils and a special M2 cytological feature. This new correlation between 12p abnormalities and M2-baso phenotype is presented. The localisation of c-k ras 2 genes at the same 12p site suggests a possible mutation of this c-oncogene.
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