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  • Title: Secondary hypertension and neurofibromatosis: bilateral renal artery stenosis and coarctation of the abdominal aorta.
    Author: Tenschert W, Holdener EE, Haertel MM, Senn H, Vetter W.
    Journal: Klin Wochenschr; 1985 Jul 01; 63(13):593-6. PubMed ID: 3928961.
    Abstract:
    A 34-year-old white man with generalized neurofibromatosis was found to have severe renal vascular hypertension due to a coarctation of the abdominal aorta and bilateral renal artery stenosis with saccular aneurysms. Increased renal venous renin activity showed the active involvement of the renin-angiotensin system in maintaining the hypertension. Because the patient refused surgical treatment, antihypertensive treatment with Captopril, a specific inhibitor of the angiotensin converting enzyme was used, resulting in normal blood pressure being restored over an 18 month observation period.
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