These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Comparative study of microepineurial anastomoses with the use of CO2 laser and suture techniques in rat sciatic nerves: Part 1. Surgical technique, nerve action potentials, and morphological studies.
    Author: Fischer DW, Beggs JL, Kenshalo DL, Shetter AG.
    Journal: Neurosurgery; 1985 Aug; 17(2):300-8. PubMed ID: 3929156.
    Abstract:
    The possibility of utilizing the CO2 laser for neural anastomoses was investigated in a rat sciatic nerve model. One nerve in each animal was acutely divided and anastomosed using 10-0 nylon epineurial sutures, while the opposite side was joined by "welding" the opposed nerve ends together with CO2 laser pulses. The surgical incisions were reexplored 60 days postoperatively, action potentials were recorded across the anastomoses, and the nerves were removed for light and electron microscopy. The operative patency rate in the suture group was 100%, compared to 87% in the laser group. Among those animals with bilaterally intact nerves, action potentials could be recorded across the anastomotic site in 78% of the sutured preparations and in 85% of nerves spot-welded with the CO2 laser. Morphological studies showed a greater degree of scar tissue formation and constriction in the anastomotic zone of the nerves joined by sutures than was present in laser-treated animals. We believe these preliminary observations suggest that the CO2 laser may have a role to play in peripheral nerve surgery. Further study of this technique is warranted.
    [Abstract] [Full Text] [Related] [New Search]