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  • Title: Evidence for a GABAergic control of the exercise-induced rise in GH in man.
    Author: Steardo L, Iovino M, Monteleone P, Agrusta M, Orio F.
    Journal: Eur J Clin Pharmacol; 1985; 28(5):607-9. PubMed ID: 3930260.
    Abstract:
    The effect of the GABAergic drug sodium valproate (SV) on the exercise-induced release of growth hormone (GH) was investigated in 10 healthy males. The exercise test consisted of using a stationary bicycle ergometer at 450 kg/min for 20 min. SV 600 mg blunted the increase in GH induced by the exercise, suggesting GABAergic regulation of GH secretion in man, at least under certain physiological conditions.
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