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  • Title: Increase in enzyme activities of prostaglandin biosynthesis and catabolism by acute ureteral ligation in rat kidney.
    Author: Fukuda S, Hamasaki Y, Tai HH.
    Journal: Life Sci; 1985 Sep 30; 37(13):1249-55. PubMed ID: 3930905.
    Abstract:
    Acute ureteral obstruction increased cyclooxygenase, thromboxane and prostacyclin synthases and NAD+-linked 15-hydroxyprostaglandin dehydrogenase activities in rat kidney. Significant increase in prostaglandin biosynthetic and catabolic activities may mediate some pathological consequences found in obstructive nephropathy.
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