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  • Title: Neurofibromas: location by scanning with Tc-99m DTPA. Work in progress.
    Author: Mandell GA, Herrick WC, Harcke HT, Sharkey C, Brooks KM, MacEwen GD.
    Journal: Radiology; 1985 Dec; 157(3):803-6. PubMed ID: 3933050.
    Abstract:
    The accumulation of technetium-99m diethylenetriamine pentaacetic acid (Tc-99m DTPA) in benign soft-tissue neurofibromatosis tumors is reported. In a series of 16 patients with clinical stigmata of neurofibromatosis, 28 sites of abnormal soft-tissue localization of the isotope observed scintigraphically were documented to be sites of soft-tissue tumor by clinical and/or radiographic (predominantly computed tomographic) correlations. The smallest lesion detected was a 1.5-cm subcutaneous neurofibroma. Normal physiologic nonrenal distribution of the Tc-99m DTPA was established by scintigraphic imaging of a control population.
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