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  • Title: Hemolytic disease of the newborn due to anti-C and anti-G masquerading as anti-D.
    Author: Yesus YW, Akhter JE.
    Journal: Am J Clin Pathol; 1985 Dec; 84(6):769-72. PubMed ID: 3934960.
    Abstract:
    After several transfusions with D-negative blood, an O Rh-negative women was apparently sensitized to the C and D antigens. In her prenatal workup, it became evident that she had in fact not been sensitized to D but to G, which initially appeared as anti-D plus anti-C. This sensitization pattern is an unusual occurrence in itself. Moreover, the fetus was affected significantly and was delivered at 32 1/2 weeks with moderate hemolytic disease of the newborn. Consideration is given to points regarding current methods of screening Rh-negative women for transfusion, the use of anti-Rh immune globulin in patients sensitized to anti-C and anti-G, medicolegal implications, and continuous attention to the risk-benefit ratio in decisions to use transfusions.
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