These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of verapamil and sodium cromoglycate on bronchoconstriction induced by isocapnic hyperventilation.
    Author: Rafferty P, Fergusson RJ, Tweeddale PM, Biggs BA, Grant IW.
    Journal: Clin Allergy; 1985 Nov; 15(6):531-4. PubMed ID: 3935343.
    Abstract:
    Twenty-four patients who were known to develop bronchoconstriction in response to isocapnic hyperventilation (IH) took part in a double-blind, placebo-controlled trial to assess the effects of verapamil (5 mg) and sodium cromoglycate (SCG) 20 mg in the prevention of IH-induced bronchoconstriction. Both drug and placebo were inhaled in dry powder form and responses were assessed by serial measurements of forced expiratory volume in 1 sec (FEV1). Sodium cromoglycate was shown to offer significant protection whereas verapamil powder provoked bronchoconstriction in over 40% of patients and these patients appeared to be those with more marked degrees of bronchial reactivity.
    [Abstract] [Full Text] [Related] [New Search]