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  • Title: Mediators and asthma.
    Author: Barnes PJ.
    Journal: Br J Hosp Med; 1985 Dec; 34(6):339-44. PubMed ID: 3936563.
    Abstract:
    Several mediators produced by various inflammatory cells have now been implicated in asthma. They may contribute to the pathology of asthma by contracting airway smooth muscle, stimulating mucus secretion, and promoting bronchial oedema and chemotaxis of inflammatory cells. Because many mediators interact, antagonism of any single mediator is unlikely to have a major clinical effect.
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