These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Taste response to 2,5-anhydro-D-hexitols; rigid stereospecificity of the furanose site in the sugar receptor of the flesh fly.
    Author: Shimada I, Horiki H, Ohrui H, Meguro H.
    Journal: J Comp Physiol A; 1985 Oct; 157(4):477-82. PubMed ID: 3939243.
    Abstract:
    2,5-Anhydro-D-mannitol with a fixed furanose ring stimulated the sugar receptor of the flesh fly and reacted with the furanose site. This is the first direct evidence that a furanose can stimulate the sugar receptor and supports strongly the assumption that beta-D-fructofuranose is the only stimulatory component in the solution of D-fructose. Rigid stereospecificity of the furanose site in the sugar receptor is discussed according to the effectiveness of various synthetic 2,5-anhydro-D-hexitols and related compounds. At least four receptor sites are concluded to be in a single sugar receptor: a pyranose (P) site, a furanose (F) site, an aliphatic carboxylate (R) site and an aromatic amino acid (Ar) site.
    [Abstract] [Full Text] [Related] [New Search]