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  • Title: The association of IgG heavy-chain allotypes (Gm) with Graves' disease in Hungary.
    Author: Kozma L, Stenszky V, Kraszits E, Balazs C, Farid NR.
    Journal: Exp Clin Immunogenet; 1985; 2(3):154-7. PubMed ID: 3939975.
    Abstract:
    In an Eastern Hungarian population of patients, we sought to confirm an association with IgG heavy-chain allotypes (Gm) with Graves' disease. We found an increase in the phenotype fb (chi 2(1) = 4.7, p less than 0.05) among the patient group compared to controls. The influence of Ig-linked genes to Graves' disease susceptibility is, thus, dose-dependent. We found no interaction between fb homozygosity and HLA-DR3 positivity in Graves' disease susceptibility.
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