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  • Title: The release of enterokinase following secretin and cholecystokinin-pancreozymin in man.
    Author: Moss S, Birch GR, Lobley RW, Holmes R.
    Journal: Scand J Gastroenterol; 1979; 14(8):1001-7. PubMed ID: 394301.
    Abstract:
    The release of enterokinase into human duodenal fluid was studied after intravenous injections of secretin and cholecystokinin-pancreozymin (CCK-PZ). In five control subjects there was a significant release of the enzyme after stimulation with either hormone. A similar release of enterokinase was observed after hormonal stimulation in three patients with total biliary obstruction and in four patients with pancreatic exocrine insufficiency. These results suggest that the hormone-mediated release of enterokinase is independent of bile salts and trypsin in man. This release of enterokinase into duodenal fluid may be physiologically important in protein digestion.
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