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  • Title: Clinical application of pre-programmed insulin infusion: continuous subcutaneous insulin therapy with a portable infusion system.
    Author: Pickup JC, Viberti GC, Keen H, Parsons JA, Alberti KG.
    Journal: Horm Metab Res Suppl; 1979; (8):202-4. PubMed ID: 395081.
    Abstract:
    Strict control of blood glucose was achieved by continuous subcutaneous insulin infusion with a specially adapted Mill Hill Infuser for 3-4 days. This led to normalisation of some of the intermediary metabolites. In a few patients, subcutaneous infusions have been carried out for periods up to 3 months with home monitoring of blood glucose, without infection or lipodystrophy. Short-term improvement of metabolic control was associated with recovery of abnormal renal glomerular permeability to albumin.
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