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  • Title: Iron mobilization from ferritin using alpha-oxohydroxy heteroaromatic chelators.
    Author: Kontoghiorghes GJ.
    Journal: Biochem J; 1986 Jan 01; 233(1):299-302. PubMed ID: 3954731.
    Abstract:
    Several alpha-oxohydroxy heteroaromatic chelators have been shown to mobilize iron from horse spleen ferritin. Although the reactions were slow, taking up to 3 days to reach completion, the amounts of iron mobilized were higher than those reported for other chelators. These results increase the prospects for the clinical use of alpha-oxohydroxy chelators in the treatment of iron overload.
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