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  • Title: Dopamine-beta-hydroxylase (DBH) and homovanillic acid (HVA) in autistic children.
    Author: Garnier C, Comoy E, Barthelemy C, Leddet I, Garreau B, Muh JP, Lelord G.
    Journal: J Autism Dev Disord; 1986 Mar; 16(1):23-9. PubMed ID: 3957856.
    Abstract:
    In the present study, plasma DBH activity and urinary HVA levels were measured in 19 autistic and 15 normal children. DBH activity was significantly elevated in the 8 less retarded autistic patients. In this subgroup, a negative correlation was found between plasma DBH and urinary HVA levels. These results support the hypothesis of a possible involvement of brain catecholamine dysfunction in the production of autistic symptoms.
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