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  • Title: [A study of the early stages of biliary extrahepatic ducts organogenesis in the rat (Rattus norvegicus albinos) (author's transl)].
    Author: Costiou P, Junquera P, Schowing J.
    Journal: Arch Anat Histol Embryol; 1979; 62():73-85. PubMed ID: 395905.
    Abstract:
    In the early stages of morphogenesis, the hepatic diverticulum of the rat develops as in other mammals. Its anterior part gives rise to epithelial cell-cords bound by an epithelial primary plate to a single hepatic duct which joins the liver to the midgut. The interlobular bile-ducts develop from secondary epithelial plates which derivate from the primary one. The posterior part of diverticulum gives rise to a duct which may be assimilated by its position, structure and evolution, to the initial cystic duct of other mammals. This duct never participates to the formation of biliary extrahepatic ducts, but builds the ventral pancreas. Cellular necrosis is observed in relation with the development of the anterior part of diverticulum during the three first days of the hepatic morphogenesis.
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