These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Chemotherapeutically active anthraquinones. II. Aminomethylanthraquinones.
    Author: Winkelmann E, Raether W.
    Journal: Arzneimittelforschung; 1986 Feb; 36(2):234-47. PubMed ID: 3964330.
    Abstract:
    Basically substituted 2,6- and 2,7-bis-amino-methylanthraquinones have a pronounced in vitro and in vivo effect against Entamoeba hystolytica (extraintestinal amoebiasis in golden hamsters) and marked interferon-inducing properties. In 2,6- and 2,7-bis-aminomethyl-anthraquinones only the introduction of hydroxyl groups in 1,5 or 1,8 position led to an additional high systemic activity against Trichomonas foetus in NMRI mice, but it also resulted in the loss of the interferon-inducing effect. Both substance classes included several compounds whose effects against E. histolytica or T. foetus were either comparable or superior to those of standard compounds ornidazole and tinidazole.
    [Abstract] [Full Text] [Related] [New Search]