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  • Title: Use of clonazepam in two cases of acute mania.
    Author: Freinhar JP, Alvarez WH.
    Journal: J Clin Psychiatry; 1985 Jan; 46(1):29-30. PubMed ID: 3965440.
    Abstract:
    Two cases of mania, one psychotic and one nonpsychotic, were treated with clonazepam, 4 mg p.o. q.i.d. In the nonpsychotic patient, complete alleviation of manic symptomatology was noted with use of clonazepam. The psychotic patient showed a reduction in manic behavior during clonazepam therapy, but without concomitant effect on psychotic features. Implications for the use of this novel psychopharmacologic agent are discussed and a possible mechanism of action is proposed.
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