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  • Title: Pattern of the primary and secondary antibody responses elicited by TNP-LPS in mice.
    Author: Huchet R.
    Journal: Int Arch Allergy Appl Immunol; 1985; 76(2):182-4. PubMed ID: 3967945.
    Abstract:
    Trinitrophenylated lipopolysaccharide (TNP-LPS) at high doses (30 micrograms) induces thymus-independent IgM and IgG anti-TNP responses. At low doses (0.3 microgram) it elicits only an IgM anti-TNP response. TNP-LPS primes for a secondary response of IgG type only when given at high doses (30 micrograms): this response is thymus dependent.
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