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  • Title: [Extensive intra-abdominal tumor masses in primary osteomyelofibrosis].
    Author: Krause MW, Maire R.
    Journal: Schweiz Med Wochenschr; 1985 Jan 05; 115(1):24-9. PubMed ID: 3969539.
    Abstract:
    A 65-year-old female suffering from agnogenic myeloid metaplasia developed multiple gradually growing tumor masses in the abdomen 4 years after splenectomy. At death, the abdominal cavity was mainly dominated by these masses. At autopsy, histological examination of the tumor tissue revealed extramedullary hematopoiesis with an intensive fibroblastic reaction whose appearance was very similar to the fibrous bone marrow. Pathogenesis, complications and therapy of this unusual manifestation of extramedullary hematopoiesis in agnogenic myeloid metaplasia are discussed.
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