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  • Title: [Clinical studies on the reaction of the skin to various doses of Su-polysaccharide in cancer patients].
    Author: Sato M, Sakai K, Kimura S, Tamaki Y, Kiyasu Y, Joko Y, Ogoshi T.
    Journal: Gan To Kagaku Ryoho; 1985 Feb; 12(2):245-9. PubMed ID: 3970550.
    Abstract:
    The reaction of skin to 10-micrograms and 20-micrograms quantities of Su-polysaccharide (Su-Ps) were examined in 117 patients with cancer, and the results obtained were as follows. Reaction was a little greater to the 20-micrograms dose than to the 10-micrograms dose, but the two parameters were much correlated with each other. The rates of patients showing positive reactions to each dose were 30.8% for 10-micrograms and 34.2% for 20-micrograms. The reactions were augmented by administration of OK-432. The augmentation of skin reaction by OK-432 was more prominent at 20-micrograms doses than at 10-micrograms doses, therefore appearing to be Su-polysaccharide dose-dependent. The ideal Su-polysaccharide dose for Su-Ps skin reaction thus seemed to be 20-micrograms.
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