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  • Title: [Effects of long-term treatment with L-carnitine on dyslipemia in hemodialysis patients].
    Author: Dionisio P, Bergia R, Caramello E, Graziola M, Valenti M, Bajardi P, Barbera L, Voglino F.
    Journal: Minerva Med; 1985 Feb 18; 76(6):229-34. PubMed ID: 3974937.
    Abstract:
    The effect of long-term intravenous administration of L-carnitine on the lipid pattern of 18 patients on intermittent haemodialysis has been evaluated. Serum levels of carnitine were assayed at the beginning and after 4 months of treatment: no significant change was observed. At the end of our investigation, we found a significant reduction of HDL-cholesterol and a significant increase of triglyceride levels, compared with basal values. On the contrary cholesterol levels did not change. Five of the patients though behaved as responders to the treatment: their triglyceride levels decrease while their carnitine values rose significantly. The Authors discuss the therapeutic importance of L-carnitine and its possible influence on dyslipaemia of uremic haemodialysed patients.
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