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  • Title: Human marrow stromal cells in short-term semi-solid bone marrow culture in aplastic anaemia.
    Author: Reynolds M, McCann SR.
    Journal: Scand J Haematol; 1985 Feb; 34(2):101-10. PubMed ID: 3975567.
    Abstract:
    A short-term methylcellulose technique was used to study the proliferation of marrow-derived stromal, erythroid and myeloid colonies from normal controls and from patients with aplastic anaemia. There was a significant reduction in all colony types in patients with aplastic anaemia when compared with normal controls. In 4 patients who achieved remission following treatment with ATG + oxymetholone or with oxymetholone alone there was a return to normal range of stromal colonies and also of CFU-E. There was no change in the numbers of BFU-E's and only a slight increase in the numbers of CFU-C's.
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