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  • Title: Induction and detection of a third isometallothionein (metallothionein-II') in rat liver.
    Author: Suzuki KT, Uehara H, Sunaga H, Shimojo N.
    Journal: Toxicol Lett; 1985 Jan; 24(1):15-20. PubMed ID: 3975925.
    Abstract:
    A third isometallothionein was shown to be present during metallothionein synthesis, particularly following induction by zinc (Zn). It appeared to be closely related to metallothionein-II and the relative amount decreased with time, with only a minor peak after repeated cadmium (Cd) loading. On-line column switching by high-performance liquid chromatography (HPLC)-atomic absorption spectrophotometry (AAS) is effective in analysing and characterizing isometallothioneins.
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