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  • Title: [Pathology and pathogenesis of multiple sclerosis from the viewpoint of neurologic disease research].
    Author: Seitelberger F.
    Journal: Wien Med Wochenschr; 1985 Jan 31; 135(1-2):6-7. PubMed ID: 3976241.
    Abstract:
    The pathology of multiple sclerosis (MS) is characterized by the trias: inflammation, primary demyelination and reactive gliosis. However, besides these obligatory alterations a high inter- and intraindividual variability of structural aspects is found in MS lesions. Recent experimental studies in a model disease for MS, in chronic relapsing experimental allergic encephalomyelitis, provide a better understanding of the dynamics of lesions development in MS brains.
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