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  • Title: Topical immunology of nasal allergy and mucosal IgE antibodies.
    Author: Ohashi Y, Nakai Y, Kuroki K, Nakata J, Maruoka K, Ikeoka H, Takeichi N, Kihara S.
    Journal: Arch Otorhinolaryngol; 1985; 241(2):169-74. PubMed ID: 3977769.
    Abstract:
    In the present study, the in vitro tissue-radioallergosorbent test (t-RAST) was performed in two groups of patients: one with perennial attacks of sneezing, serous hypersecretion and nasal congestion, the other with nasal congestion only. The results obtained were compared with those obtained by a series of conventional allergy tests. We then found that t-RAST provided objective data comparable to those obtained with serum-RAST and that the t-RAST is a reliable means of quantitatively detecting specific IgE antibodies in the nasal mucosa. t-RAST is of special value to diagnosticians because it is able to discern unequivocally and easily those patients with localized nasal allergy.
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