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  • Title: [Light optical and electron microscopic studies of the tumor cells in rats exposed to vinblastine against a background of increased activity of the anticoagulating system].
    Author: Kolomina SM, Chentsov IuS, Kalishevskaia TM, Kudriashov BA, Murasheva MI.
    Journal: Eksp Onkol; 1985; 7(1):60-4. PubMed ID: 3979343.
    Abstract:
    It is shown that the damage of sarcoma 45 cells at different stages of cell life cycle occurs under the effect of vinblastine treatment against a background of higher activity of the blood anticoagulating system. A decrease in the mitotic activity, mitosis accumulation in prophase and especially in the metaphase as well as essential changes in the interphase cell ultrastructure are detected.
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