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  • Title: Cadaveric graft survival, clinical course, blood transfusion, HLA (A and B) match, and DR match in adult patients transplanted in one centre.
    Author: van Hooff JP, van Es A, Persijn GG, van Hooff-Eykenboom IJ, Kalff MW, van Rood JJ, de Graeff J.
    Journal: Proc Eur Dial Transplant Assoc; 1979; 16():359-65. PubMed ID: 398507.
    Abstract:
    The influence of blood transfusions, HLA, A and B, DR matching was studied in adult patients transplanted in one centre. The conclusions were: 1. Pre-transplant blood transfusion(s) are a prerequisite for graft acceptance. 2. In transfused patients with no HLA A and B mismatch, there is only 8% graft loss due to irreversible rejection. 3. In transfused patients with a functioning graft after six months, a decrease in the number of reversible rejection crises is observed in patients with no HLA A and B mismatch or with identity for HLA B7 or HLA B8. 4. Identity for HLA B7 or B8 also gives a higher chance of a late onset of the first rejection crisis.
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