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  • Title: Kathon CG: cosmetic allergy and patch test sensitization.
    Author: de Groot AC, Liem DH, Weyland JW.
    Journal: Contact Dermatitis; 1985 Feb; 12(2):76-80. PubMed ID: 3987260.
    Abstract:
    Three cases of contact allergy to Kathon CG, a preservative for cosmetics and toiletries containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are presented. In two patients, Kathon CG was contained in a moisturizing cream, and the third was sensitized by a diagnostic patch test. Although it has been used extensively in cosmetics and toiletries for 9 years in Europe and 4 years in the USA, these appear to be the first case reports of non-occupational sensitization to Kathon CG.
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