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  • Title: Effect of acetazolamide (Diamox) on tear secretion.
    Author: van Agtmaal EJ, Thörig L, van Haeringen NJ.
    Journal: Doc Ophthalmol; 1985 Jan 31; 59(1):77-80. PubMed ID: 3987501.
    Abstract:
    The side effects of acetazolamide (Diamox) on lacrimation were measured in rats by means of the cotton-thread tear test. After a daily oral 1-mg dose (administered for five days), comparable to the dose used for adult humans on a drug-to-bodyweight basis, tear production remained unaffected but the lacrimal peroxidase secretion decreased by 60% of the baseline level. After withdrawal of acetazolamide the peroxidase secretion returned to the baseline level.
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