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  • Title: Changes in brush-border enzyme activities of intestinal epithelial cells isolated from the villus-crypt axis during the early phase of alloxan diabetes in rats.
    Author: Nakabou Y, Ikeuchi K, Minami H, Hagihira H.
    Journal: Experientia; 1985 Apr 15; 41(4):482-4. PubMed ID: 3987870.
    Abstract:
    The sucrase activity in enterocytes isolated from the villus crypt axis was found to increase in all regions of the villus from day 2 after induction of diabetes, and the increase continued until day 4. In contrast, alkaline phosphatase activity increased mainly in the apical one-third of the villus-crypt column, and the increase occurred abruptly on day 4 with increase in food intake.
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