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  • Title: Sphenoethmoidal encephalomeningocele and midline anomalies of face and brain.
    Author: Tada M, Nakamura N.
    Journal: Hokkaido Igaku Zasshi; 1985 Jan; 60(1):48-56. PubMed ID: 3988232.
    Abstract:
    An autopsy case of sphenoethmoidal encephalomeningocele associated with anophthalmia, agenesis of the corpus callosum, cleft palate and nasal septum defect is presented. A small colloid cyst and a cyst of unknown nature were found in the third ventricle. Based on a review of the literature, a peculiar association of sphenoethmoidal encephalomeningocele with callosal defect and midline facial anomalies seems not to be fortuitous and we proposed to call it "Sakoda complex" as a distinctive disease entity. Pathogenetic mechanism and significance of separation of this syndrome are discussed from a embryological standpoint. Anophthalmia and the cyst of unknown nature are interpreted as midline anomalies that may be attributed to the same pathogenetic cause.
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