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  • Title: Effects of dietary protein restriction on the course of early renal failure.
    Author: Zakar G.
    Journal: Proc Eur Dial Transplant Assoc Eur Ren Assoc; 1985; 21():600-3. PubMed ID: 3991551.
    Abstract:
    Two groups of patients with histologically proven glomerulonephritis and chronic renal failure were studied. Group 1 comprised 28 patients with an endogenous creatinine clearance of 66ml/min, daily protein excretion of 1.7g. These patients were maintained for eight to 18 months on a diet containing about 40Kcal/kg and 1g/kg of protein. Phosphorous and calcium intake were unrestricted. Group 2 had 32 patients with a mean creatinine clearance of 60ml/min and daily protein excretion of 1.8g. They followed no specific dietary regimen for six to 14 months. Their dietary calorie and protein intakes averaged 30Kcal/kg and 70g respectively. At the end of the observation period creatinine clearance values of Group 1 averaged 74ml/min, the daily protein excretion amounted to 1.1g. Values for Group 2 averaged 53ml/min and 1.9g respectively. Moderate dietary restriction of protein alone results in improving creatinine clearance values and a decreased protein excretion in the early stages of chronic renal failure in patients with glomerulonephritis.
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