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  • Title: [Specific contribution of dietary polyunsaturated fatty acids of the n-3 series to the development of nervous system membranes].
    Author: Bourre JM, Chanez C, Dumont O, Durand G, Faivre A, Nouvelot A, Pascal G, Piciotti M.
    Journal: Reprod Nutr Dev (1980); 1985; 25(1B):335-40. PubMed ID: 3992003.
    Abstract:
    Polyunsaturated fatty acids, especially omega 3 fatty acids, made a specific contribution to the nervous tissue. Retarded intrauterine growth caused a twofold reduction in the oligodendrocyte ratio of omega 3/omega 6 while the same ratio increased by more than twofold in the neurons. A fatty acid-poor diet composed of arachid or sunflower oil dramatically altered the composition of cells and subcellular particles when compared with a soya or rapeseed oil diet containing omega 3 fatty acids; phosphatidylethanolamine was particularly affected. Nerve cell culture showed that brain essential fatty acids are probably docosahexaenoic acid and arachidonic acid.
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