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Title: The effects of post-heparin plasma lipases on anti-Xa clotting activity. Author: Williams SP, Barrowcliffe TW. Journal: Thromb Res; 1985 Feb 01; 37(3):371-7. PubMed ID: 3992526. Abstract: The effects of hepatic triglyceride lipase (HTGL) and lipoprotein lipase (LPL) on the anti-Xa clotting activity of plasma were studied. LPL had no effect, but HTGL enhanced anti-Xa activity. This enhancement was shown to be due to a time-dependent action of HTGL on lipoproteins. These results could explain the increases in anti-Xa clotting activity previously observed after injection of heparin analogues, SSHA and SP54, which are potent releasers of lipase enzymes.[Abstract] [Full Text] [Related] [New Search]