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  • Title: Pathochemical study of a case of hereditary cerebral degenerative disease--lipopigment accumulation and peroxidase deficiency in brain.
    Author: Yamaguchi S, Okuno A, Eto Y, Maekawa K.
    Journal: Tohoku J Exp Med; 1985 Feb; 145(2):223-9. PubMed ID: 3992585.
    Abstract:
    Ultrastructural study of autoptic cerebral tissue from a patient with hereditary degenerative disease of the nervous system revealed lipofuscin-like bodies and variable sized osmiophilic granular masses in neurons. Autofluorescent granules were also found in neurons. Biochemical study demonstrated a deficiency of diaminobenzidine peroxidase and the accumulation of lipopigment in cerebral tissue.
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