These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Comparison of the level of sister chromatid exchanges and chromosome aberrations induced by chemical mutagens in vitro and in vivo].
    Author: Shcheglova EG, Chebotarev AN.
    Journal: Tsitol Genet; 1985; 19(1):20-3. PubMed ID: 3992652.
    Abstract:
    The paper presents results of a study of a dose dependence of induction of SCE and chromosomal aberrations at the exposure of human lymphocytes in vitro and bone marrow cells of mice in vivo to 5 alkylating chemicals. The efficiency of SCE induction in vitro is found to be 300-30 times as high as that of arising of chromosomal aberrations. The same regularity is observed in experiments in vivo, but the ratio is reduced to 60-20 times.
    [Abstract] [Full Text] [Related] [New Search]