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  • Title: [Quantity and trace elements in callus in secondary fracture healing; animal experiment study].
    Author: Klug W, Dude H, Schulze M, Gabsch HC.
    Journal: Z Exp Chir Transplant Kunstliche Organe; 1985; 18(1):25-32. PubMed ID: 3993134.
    Abstract:
    The quantitative analysis of quantity elements and trace elements in the callus tissue of tibial fractures was carried out in 120 adult rabbits during the secondary bone fracture healing. The processing of the callus and the analysis methods of the inorganic elements were demonstrated. The trace elements copper and zinc are available much more compared with the quantity elements in the callus tissue during the acidotic early phase of the fracture healing. Copper and zinc are necessary for synthesis of the bone substance and the enzymes. The phosphorus concentration increased in a three-phasic way in the callus during the fracture healing. Phosphorus is prematurely enriched in the callus quantitatively stronger than calcium.
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