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  • Title: Immunological studies in neonates with spina bifida.
    Author: Puri P, Reen DJ, Browne O, Blake P, Guiney EJ.
    Journal: Z Kinderchir Grenzgeb; 1979 Dec; 28(4):336-9. PubMed ID: 399410.
    Abstract:
    Fifteen neonates with spina bifida were investigated prior to surgery for T and B lymphocytes subpopulations and mitogen responsiveness to PHA. Results were compared to similar studies in 30 normal healthy neonates. The mean percentage of T-lymphocyes in spina bifida patients was 44.6% compared to 48.9% in normal neonates. A normal dose response to PHA was obtained in all patients. These results suggest no impairment of lymphocyte function in neonates born with spina bifida.
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