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  • Title: Skeletal muscle antibodies in patients with a thymic tumour but without myasthenia gravis.
    Author: Gilhus NE, Aarli JA, Janzen RW, Otto HF, Fasske E, Matre R.
    Journal: J Neuroimmunol; 1985 May; 8(2-3):69-78. PubMed ID: 3998123.
    Abstract:
    Sera from 9 patients with a primary thymic tumour but without myasthenia gravis (MG) at the time of thymectomy were examined for skeletal muscle antibodies. Antibodies to a citric acid extract (CA), associated with the presence of a thymic lymphoepithelioma in MG patients, were detected in 3 sera. AChR antibodies were detected in 5 sera, the concentration markedly elevated in 1 of them. Sarcolemmal and cross-striational antibodies were detected in 2 and 3 sera, respectively. Four of the 5 patients with thymic tumours other than a lymphoepithelioma had AChR antibodies, and 3 of them also had CA antibodies.
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