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  • Title: Monoamine and diamine oxidative deamination in the longitudinal smooth muscle of guinea pig ileum.
    Author: Banchelli G, Raimondi L, Ignesti G, Pirisino R, Buffoni F.
    Journal: Med Biol; 1985; 63(1):34-9. PubMed ID: 3999819.
    Abstract:
    The longitudinal smooth muscle of guinea pig ileum contains three different types of oxidative deaminating enzymes: monoamine oxidase types A and B, diamine oxidase and a soluble clorgyline-deprenyl-resistant benzylamine oxidase. These enzymes have different subcellular locations. The longitudinal smooth muscle of guinea pig ileum oxidatively deaminates beta-phenylethylamine at a much higher rate than benzylamine. beta-Phenylethylamine is a good substrate for monoamine oxidase type B but also for the soluble clorgyline-deprenyl-resistant benzylamine oxidase. On the other hand, benzylamine is oxidised by mitochondrial monoamine oxidase, by the clorgyline-deprenyl-resistant enzyme and by diamine oxidase.
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