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  • Title: Plasma warfarin concentrations after a massive overdose.
    Author: Hackett LP, Ilett KF, Chester A.
    Journal: Med J Aust; 1985 Jun 10; 142(12):642-3. PubMed ID: 4000042.
    Abstract:
    The plasma pharmacokinetics of warfarin were studied in a patient who took an overdose of warfarin (2000 mg by mouth), together with 25 X 10(4) units of heparin administered subcutaneously. The plasma warfarin level fell rapidly (half-life, 21.7 h), and there was no convincing evidence for dose-dependency in its disposition.
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