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  • Title: Genotoxicity of ptaquiloside, a bracken carcinogen, in the hepatocyte primary culture/DNA-repair test.
    Author: Mori H, Sugie S, Hirono I, Yamada K, Niwa H, Ojika M.
    Journal: Mutat Res; 1985; 143(1-2):75-8. PubMed ID: 4000145.
    Abstract:
    The genotoxicity of ptaquiloside (PT), recently isolated from bracken fern and shown to be carcinogenic, was examined by means of the hepatocyte primary culture/DNA-repair test. PT elicited clear unscheduled DNA synthesis with a dose-response effect. The result indicates that PT is a genotoxic carcinogen.
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