These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of malotilate on paracetamol-induced hepatotoxicity.
    Author: Younes M, Siegers CP.
    Journal: Toxicol Lett; 1985 May; 25(2):143-6. PubMed ID: 4002245.
    Abstract:
    Malotilate (diisopropyl-1,3-dithiol-2-ylidenemalonate) prevented liver damage induced by paracetamol in male mice only when given 1 h prior to the hepatotoxic agent. Furthermore, it partially inhibited paracetamol-induced glutathione depletion in mouse liver, indicating that the antihepatotoxic activity of malotilate is related to an interaction with the bioactivation of paracetamol.
    [Abstract] [Full Text] [Related] [New Search]