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  • Title: The effect of ethanol consumption on folate polyglutamate biosynthesis in the rat.
    Author: Keating JN, Weir DG, Scott JM.
    Journal: Biochem Pharmacol; 1985 Jun 01; 34(11):1913-6. PubMed ID: 4004907.
    Abstract:
    Contrary to previous studies, the folate polyglutamate chain length in the rat liver appears to be unaffected by ethanol ingestion for periods of 2-13 weeks. The appearance of short chain length folates after 13 weeks has been shown to arise as a result of increased in vitro folate polyglutamate breakdown during extraction due to a greater release of lysosomal conjugase in these animals.
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