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  • Title: Fornix-fimbria section and the partial reinforcement extinction effect.
    Author: Feldon J, Rawlins JN, Gray JA.
    Journal: Exp Brain Res; 1985; 58(3):435-9. PubMed ID: 4007086.
    Abstract:
    Rats were trained to run in an alley for food reward given on every trial (continuous reinforcement, CR) or on a random 50% of trials (partial reinforcement, PR) and were then extinguished. Sham-operated controls showed the normal partial reinforcement extinction effect (PREE), in that PR-trained animals were significantly more resistant to extinction than CR-trained animals. The PREE was significantly reduced by lesions of the fornix-fimbria. The reduction was largely a consequence of a reduction in resistance to extinction in PR-trained rats with fimbria-fornix lesions. These results are discussed in the light of other experiments that have studied disconnections in the septo-hippocampal system.
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