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  • Title: Characterization of blood group active glycopeptides derived from porcine kidneys.
    Author: Munakata H, Isemura M, Sato N, Kikuchi M, Yosizawa Z.
    Journal: Int J Biochem; 1985; 17(3):301-8. PubMed ID: 4007242.
    Abstract:
    Sialoglycopeptide fractions were prepared from the pronase digest of porcine kidneys by DEAE-Sephadex A-25 column chromatography and gel-filtration through Sephadex G-100. Their chemical compositions and large molecular size suggested that these glycopeptides were derived from mucin-type glycoprotein(s). The results of the beta-elimination reaction indicated that they have the O-glycosidic linkages between N-acetylgalactosamine and serine/threonine. The glycopeptides exhibited blood group A and H activities. The present study revealed that the porcine kidney contains the blood group antigens of glycoprotein nature.
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